In this article, Charles Spurgeon presents a talk, abridged and adapted by Peter Masters. Spurgeon uses Psalm 23 to examine the experience of depression and its cure in the Lord’s mercy. He argues that desponding people are to be viewed with compassion, and if those who blame them furiously could once know what depression is, they would realize the cruelty of scattering reproof where comfort is needed. Spurgeon continues that the footsteps of the holy are in the valley of weeping. No sin is necessarily connected with sorrow of heart, for Jesus Christ our Lord once said, ‘My soul is exceedingly sorrowful, even unto death.’ Spurgeon concludes, there was no sin in Him, and consequently none in His deep depression.